Automatic Transformation of Membrane‐Type Electronic Devices into Complex 3D Structures via Extrusion Shear Printing and Thermal Relaxation of Acrylonitrile–Butadiene–Styrene Frameworks

This work demonstrates a means of automatic transformation from planar electronic devices to desirable 3D forms. The method uses a spatially designed thermoplastic framework created via extrusion shear printing of acrylonitrile–butadiene–styrene (ABS) on a stress‐free ABS film, which can be laminated to a membrane‐type electronic device layer. Thermal annealing above the glass transition temperature allows stress relaxation in the printed polymer chains, resulting in an overall shape transformation of the framework. In addition, the significant reduction in the Young's modulus and the ability of the polymer chains to reflow in the rubbery state release the stress concentration in the electronic device layer, which can be positioned outside the neutral mechanical plane. Electrical analyses and mechanical simulations of a membrane‐type Au electrode and indium gallium zinc oxide transistor arrays before and after transformation confirm the versatility of this method for developing 3D electronic devices based on planar forms.     

Characteristics of fat,and saponin and tannin contents of 11 varieties of rambutan (Nephelium lappaceum L.) seed

Rambutan seed is discarded during fruit processing. However, the seed contains a considerable amount of crude fat. Hence, the objective of this study was to determine two anti-nutritional constituents, namely saponin and tannin, and to characterize the fat of the seeds of 11 varieties of rambutan fruit. Results showed that the range of crude fat content is fairly narrow (36.13–39.13 g/100 g dried seeds). The iodine value and free fatty acid content of the fat were 38.50–50.61 g I₂/100 g fat and 0.99–2.18% as oleic acid, respectively. Oleic (33.35–46.64%) and arachidic (26.03–33.27%) acids were the main fatty acids in the fat. HPLC analysis showed that the fat comprised mainly five unknown triacylglycerols (83.94–95.33%). The melting and crystallization curves showed that the fat exhibited four to nine non-distinct peaks. The complete melting and crystallization onset temperatures of the fat were 24.8–50.6°C and 24.1–39.4°C, respectively, while the melting and crystallization enthalpies of the fat ranged from 71.2 to 141.7 J/g and from 60.4 to 88.9 J/g, respectively. At 0°C, the solid fat index of the fat ranged between 87.4% and 91.6% and the fats of some varieties melted completely at human body temperature. The saponin and tannin contents of the seed were 14.27–18.96 mg soya saponin/100 g and 4.40–26.68 mg catechin equivalent/100 g, respectively. Findings showed that rambutan seed fat has potential to be used in various sectors of food industry.     

Design and control of coaxial switching system for ion cyclotron wave resonance heating system of EAST

Ion cyclotron wave resonance heating system(ICRH) which is one of the most important auxiliary system in EAST provides conditions for heating the plasma. In order to make the whole transmission network of ICRH form the required state, the coaxial switching system was developed, which mainly consists of 11 same coaxial switches. Each coaxial switch has a controller with an RS485 communication interface and is able to switch between two states. All controllers are integrated to an RS485 hub which connects to the computer. A master computer software is developed to control the coaxial switching system so as to achieve the state needs of ICRH. Moreover, several rounds of experiments show that the coaxial switching system operates reliably. The coaxial switching system has already been applied to normal use currently.     

Analysis of surface wave behavior in corrugated piezomagnetic layer resting on inhomogeneous half-space

This paper deals with propagation of Love type waves in a Piezomagnetic layer with corrugated boundaries overlying an inhomogeneous half-space. Inhomogeneity of elastic half-space is caused due to exponential variations in elastic parameters. Dispersion relations are obtained for magnetically open and short cases. Prominent effects of inhomogeneity, layer's width and corrugation on the phase velocity of considered wave are illustrated through graphs. Some particular cases are derived and exhibited through graphs. Also the influence of undulation parameter, elastic parameter, and piezomagnetic coefficient on phase velocity of considered wave has been marked separately. The present study finds its applications in designing and optimization of Love wave sensors and Seismic Acoustic Wave (SAW) devices. Findings may also be used for analytical study of wave propagation in piezomagnetic coupled structures.     

渤海湾盆地沙垒田地区新近纪走滑断裂发育特征及其对油气富集的控制作用

沙垒田凸起地区是渤海海域西部新近系油气最为富集的区域，为了明确新近系走滑断裂发育特征及对油气富集的控制作用，依托连片高精度三维地震、钻井取心等资料，对走滑断裂类型及发育特征进行了详细刻画，并对走滑断裂与成藏要素之间的关系进行了探讨。综合研究表明：研究区发育断穿基底走滑断裂、盖层走滑断裂及伸展-走滑断裂三种不同类型走滑断裂；走滑断裂对圈闭的控制作用表现为在不同类型走滑断裂控制下，断裂带内及断裂带间形成了多种类型圈闭，其中大型披覆背斜圈闭、断鼻、断背斜圈闭为有利圈闭，小型断块圈闭为不利圈闭；走滑断裂对输导体系的控制作用体现在断裂活动控制了骨架砂体输导体系及断裂输导体系的形成发育，有利于周边凹陷成熟烃源岩排烃及运移输导；走滑断裂对储层的控制作用表现为走滑作用形成的高角度裂缝提高了储层渗透率，改善了储层物性。新近纪普遍发育的走滑断裂是研究区油气富集的主控因素。     

Inhibition of Soluble Epoxide Hydrolase Ameliorates Phenotype and Cognitive Abilities in a Murine Model of Niemann Pick Type C Disease

Niemann–Pick type C (NPC) disease is a rare autosomal recessive inherited childhood neurodegenerative disease characterized by the accumulation of cholesterol and glycosphingolipids, involving the autophagy-lysosome system. Inhibition of soluble epoxide hydrolase (sEH), an enzyme that metabolizes epoxy fatty acids (EpFAs) to 12-diols, exerts beneficial effects in modulating inflammation and autophagy, critical features of the NPC disease. This study aims to evaluate the effects of UB-EV-52, an sEH inhibitor (sEHi), in an NPC mouse model (Npc) by administering it for 4 weeks (5 mg/kg/day). Behavioral and cognitive tests (open-field test (OF)), elevated plus maze (EPM), novel object recognition test (NORT) and object location test (OLT) demonstrated that the treatment produced an improvement in short- and long-term memory as well as in spatial memory. Furthermore, UB-EV-52 treatment increased body weight and lifespan by 25% and reduced gene expression of the inflammatory markers (i.e., Il-1β and Mcp1) and enhanced oxidative stress (OS) markers (iNOS and Hmox1) in the treated Npc mice group. As for autophagic markers, surprisingly, we found significantly reduced levels of LC3B-II/LC3B-I ratio and significantly reduced brain protein levels of lysosomal-associated membrane protein-1 (LAMP-1) in treated Npc mice group compared to untreated ones in hippocampal tissue. Lipid profile analysis showed a significant reduction of lipid storage in the liver and some slight changes in homogenated brain tissue in the treated NPC mice compared to the untreated groups. Therefore, our results suggest that pharmacological inhibition of sEH ameliorates most of the characteristic features of NPC mice, demonstrating that sEH can be considered a potential therapeutic target for this disease.     

"不知火"柑橘全自动包装生产线的设计与研究

目的为了解决柑橘在实际包装过程中因于人工手动装袋、装箱等导致的效率低下问题,设计一条全自动柑橘包装生产线。方法基于“不知火”柑橘的特殊体型特征,使用传送带分级装置对其进行分级;通过倾斜皮带解决柑橘排列姿态的整理问题;经给袋式包装机装袋后,采用扭结式扎口装置对其进行封口;利用并联机器人对其进行装箱。通过计算生产节拍,合理规划每个工序的循环时间,并通过Flexsim软件对该生产线进行仿真分析与平衡优化。结果该生产线整体效率由89%提升到93%,能够正常运行且满足生产力的需求。结论该柑橘包装生产线实现了柑橘的分级、整料、装袋、装箱等工序,降低了工作强度,提高了生产效率,实现了包装过程的自动化。     

Expanding the Toolbox of R-Selective Amine Transaminases by Identification and Characterization of New Members

Amine transaminases (ATAs) are used to synthesize enantiomerically pure amines, which are building blocks for pharmaceuticals and agrochemicals. R-selective ATAs belong to the fold type IV PLP-dependent enzymes, and different sequence-, structure- and substrate scope-based features have been identified in the past decade. However, our knowledge is still restricted due to the limited number of characterized (R)-ATAs, with additional bias towards fungal origin. We aimed to expand the toolbox of (R)-ATAs and contribute to the understanding of this enzyme subfamily. We identified and characterized four new (R)-ATAs. The ATA from Exophiala sideris contains a motif characteristic for d -ATAs, which was previously believed to be a disqualifying factor for (R)-ATA activity. The crystal structure of the ATA from Shinella is the first from a Gram-negative bacterium. The ATAs from Pseudonocardia acaciae and Tetrasphaera japonica are the first characterized (R)-ATAs with a shortened/missing N-terminal helix. The active-site charges vary significantly between the new and known ATAs, correlating with their diverging substrate scope.     

鄂尔多斯盆地延长组致密砂岩储层微观孔喉特征差异及其成因

为分析不同沉积与成岩作用改造下致密砂岩储层的孔喉类型及其参数差异，利用物性、铸体薄片、扫描电镜、恒速压汞、图像粒度与X衍射实验结果，对比了鄂尔多斯盆地合水地区延长组长8储层和薛岔地区延长组长6储层的孔喉类型，定量评价了孔喉参数，揭示了形成原因。结果表明，合水地区长8储层孔隙更为发育，粒间孔、溶蚀孔、晶间孔和微孔、弱压实成因缩颈状喉道和溶蚀成因、粘土胶结成因管束状喉道含量高；薛岔地区长6储层的孔隙类型少且发育程度较差，压实成因片状、弯片状喉道含量高。两个区块的孔隙参数差异小，喉道参数差异大，前者大喉道更为发育，喉道差异大，孔喉比大，对渗透率起贡献的喉道分布范围更宽。相同渗透率条件下，前者的平均喉道半径、主流喉道半径和孔喉比大于后者。沉积水动力条件、粒度、碎屑组分、填隙物、成岩作用类型及其改造程度是两个研究区孔隙发育程度不同、喉道类型差异和孔喉参数表现出不同特征的主要原因。     

Yoghurt‐type beverage with partial substitution of milk by a chickpea extract: Effect on physicochemical and flow properties

The objective of this study was to determine the evolution of physicochemical and flow properties of a yoghurt‐type beverage partially replaced with a chickpea extract over a period of 22 days. From two chickpea extracts, Blanco Noroeste was selected for its higher protein content. Six yoghurt‐type formulations were prepared, stored at 4 °C and analysed on days 1, 8, 15 and 22. pH was 4.24–4.75, while brightness was 81.7–94.5. Flow properties of the yoghurt‐type exhibited a non‐Newtonian behaviour. From three formulations that underwent sensory evaluation, the 30:70 mix obtained the highest acceptation. This yoghurt‐type beverage exhibited characteristics similar to natural yoghurt.